Supplements in the News

Resveratrol Protects Brain
 
Published Thursday, June 1, 2006

CHIA-YI, Taiwan--Resveratrol may have neuroprotective effects, according to a study published in the Journal of Agricultural and Food Chemistry (54, 8:3126-31, 2006).


Researchers from National Chia-Yi University gave 60 adult male rats general anesthesia and randomized them to receive an ischemia treatment (bilateral ligation of carotid artery), ischemia combined with resveratrol administration (20 mg/kg) or a sham treatment. In rats not administered resveratrol, hydroxyl radical levels were elevated and severe neuronal loss occurred in the brain. In contrast, brains of animals given resveratrol had significantly increased concentrations of nitric oxide (NO) and decreased population of hydroxyl radicals. Rats given resveratrol were also shielded from reduced cerebral blood flow and neuronal loss. The researchers concluded a single dose of resveratrol could produce neuroprotective effects on cerebral ischemia-induced neuron damage through free radical scavenging and cerebral blood elevation due to NO release.

These abstracts provided courtesy of Natural Products Industry Insider, published by Virgo Publishing Inc.


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