Supplements in the News

Plant Sterols and MPOD
Published Friday, November 28, 2008

Maastricht, Netherlands—An observed reduction in serum carotenoid concentrations during 18 months of consumption did not affect macular pigment optical density (MPOD), according to a study published in the British Journal of Clinical Nutrition (DOI:10.1017/S0007114508111448). Functional foods enriched with plant sterol or stanol esters may lower serum concentrations of fat-soluble carotenoids. The double blind, placebo-controlled human intervention trial lasted 18 months while evaluating the possible effects of plant stanol and sterol esters on serum lutein/zeaxanthin concentration in relation to the MPOD. Forty-seven subjects were randomly assigned to one of the three treatment groups: margarine without added plant sterols or stanols, plant sterol-enriched margarine, or plant stanol-enriched margarine. Changes in lipid-adjusted serum lutein/zeaxanthine concentrations between baseline and study end differed significantly between the three groups (P=0.001). No differences were found in the MPOD between the three treatment groups, despite the differences in both absolute and cholesterol-standardized serum lutein/zeaxanthine concentrations.
This abstract was provided courtesy of Natural Products Industry Insider, published by Virgo Publishing Inc.

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