The American Association of Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS) has an article up that touches on the subject that their organization is principally concerned with--alleviating the pain of individuals suffering from chronic fatigue syndrome (CFS). The article is based around the findings of various Japaneseresearch groups who examined a variety of treatments, among them, vitamins and Chinese herbal medicine.
Here is what they have to say about Vitamin B:
Vitamin B complex
Itís been reported that vitamin B1 plays an important role in glucose metabolism. Vitamin B1 and vitamin B12 are also reported to play an important role in neural function. When we studied the effect of vitamin B1 on our fatigue-model mice, we noticed improvement in fatigue and performance. When we administered a high dose of vitamin B12 to patients with CFS, some of them showed an objective improvement in their sleep quality.
Since there are few adverse effects of vitamins B1 and B12, we routinely prescribe both for patients with CFS (30 to 100 mg/day of B1 and 3,000 mcg/day of B12).
Japanese Research on CFS Treatments