I3C v. Smoking
Posted Friday, December 12, 2008

Romanesco Brassica, or "Broccoflower", a variant of cauliflower

University of Minnesota scientists have identified the compound indole-3-carbinol (I3C) as a beneficial supplement for smokers. I3C is found in high levels in vegetables such as broccoli and cauliflower, and it can be administered as a supplement as well.

Using animal research models, scientists found that I3C substantially lowered the number of lung tumors in subjects who were exposed to the carcinogens which are found in tobacco smoke. The compound appears to act by inhibiting cell proliferation and enhancing programmed cell death (know as apoptosis). High levels of I3C lead to an 88% reduction of lung tumors. Tobacco smoke contains over 60 known carcinogens, and so, as always, avoiding all forms of tobacco use is the first thing you can do to ensure your health. All the same, future studies of the I3C for current and former smoker populations hold great promise.

You can see the entire study through the following link to the online version of Cancer Prevention Research: Dose-Dependent Inhibition of Tobacco Smoke Carcinogen–Induced Lung Tumorigenesis in A/J Mice by Indole-3-Carbinol

DSIB: I3C

 

 

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